Synthetic pathways of sinensetin and derivatives as an alternate source in biological activity study

Sinensetin is one of the polymethoxyflavones existed in citrus peels. The effective antioxidant, inhibitory effect inflammation, anti-diabetic and anti-cancer activity sinensetin has been revealed recently. However, amount isolated from nature source extremely low relating to needs for its vivo efficacy study. Herein we summarized alternative routes, i.e. organic synthesis associated derivatives provide a complete but concise reference preparation this class compounds as an in-depth study related molecules.